医学
酒精间隔消融
肥厚性心肌病
心室流出道梗阻
导管
导管消融
金标准(测试)
心脏病学
重症监护医学
内科学
梗阻性心肌病
外科
烧蚀
作者
Mohammed Meah,Wern Yew Ding,Robert Cooper,Rod Stables
标识
DOI:10.1016/j.cjca.2023.12.013
摘要
Hypertrophic cardiomyopathy is a common inherited cardiac condition where the myocardium progressively thickens in the absence of abnormal loading conditions. Left ventricular hypertrophy often leads to outflow tract obstruction, and this confers significant mortality and morbidity implications. Septal reduction therapies aim to relieve the obstruction in an attempt to reduce the burden of symptoms and potentially improve prognosis. However, both surgical and catheter-based approaches to septal reduction carry risks. At present, international guidelines and expert consensus statements suggest surgical myomectomy is the gold-standard treatment. In this point-counterpoint review, we discuss why in our opinion this recommendation should be reconsidered. We hope to cover the history of catheter based septal reduction therapies and the significant advances made over the last two decades. We also hope to show why we believe the current evidence shows catheter-based alcohol septal ablation is superior to surgical myomectomy.
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