Ring‐Opening Functionalization/Cyclization Reactions of Cycloalkanols under Transition‐Metal‐Free Conditions

Abstract Cycloalkanols ring‐opening transformation is one of the most valuable and wide area of research. Among the numerous methods that have been developed, transition‐metal‐free approaches have attracted great interest from both chemists and pharmacologists. This is largely due to the advantages of being environmentally benign, cost‐effective and operationally simple. Here we provide a comprehensive outline on recent advances in the synthesis of distally substituted ketones and cyclic compounds via ring‐opening transformation of cycloalkanols under transition‐metal‐free conditions.