哮喘
翻译后修饰
计算生物学
转化研究
发病机制
炎症
疾病
生物信息学
医学
免疫学
化学
生物
病理
生物化学
酶
作者
Akram Safaei,Afsaneh Arefi Oskouie
出处
期刊:Translational bioinformatics
日期:2018-01-01
卷期号:: 103-121
标识
DOI:10.1007/978-981-10-8764-6_6
摘要
Asthma is a lung inflammation disease caused by a complex interaction between the immune system and environmental factors such as allergens. A lot of research is being done on discovering new proteins and post translational modification (PTM) associated with asthma pathogenesis. This chapter illustrates updated approaches in proteins and PTM detection and associating biomarkers of asthma. We focus on approaches such as Mass Spectrometry (MS), NMR, and microarray platforms. Concepts of protein and PTMs may provide new insights in searching potential clinical biomarkers in asthma.
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