An ultrasensitive luteolin sensor based on MOFs derived CuCo coated nitrogen-doped porous carbon polyhedron

Designing high-efficiency electrocatalysts for luteolin detection is essential and vital in biological and medical field. Herein, CuCo coated nitrogen-enriched porous carbon polyhedron ([email protected]) materials are fabricated as a highly sensitive electrochemical luteolin sensor by simple and mild approach. As characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, N2 adsorption-desorption isotherms and electrochemical methods, [email protected] materials possess high specific surface area, 3D porous framework, amounts of available active sites, which all contribute to the adsorption and catalysis for luteolin. Meanwhile, vast mesoporous structure of [email protected] further affords more mass transport channels and enhances the mass transfer capacity. Thanks to above-mentioned characteristics, optimal Cu1Co3@NPCP presents superior analytical performance: a wide linear range from 0.2 nM to 2.5 μM, a ultrahigh sensitivity of 134.57 μA μM−1 surpassing to other reported catalysts previously, a low detection limit of 0.08 nM, as well as satisfactory selectivity, reproducibility, and long-term stability. This work offers an attractive catalyst derived from MOFs for constructing effective luteolin sensors.