药物发现
小分子
蛋白质降解
模块化设计
生物
化学
计算生物学
计算机科学
生物化学
操作系统
作者
Taavi K. Neklesa,Craig M. Crews
出处
期刊:Nature
[Nature Portfolio]
日期:2012-07-17
卷期号:487 (7407): 308-309
被引量:82
摘要
Most proteins in the human body are difficult targets for small-molecule drugs. This problem may have been overcome with the discovery of molecules that induce protein degradation, suggesting fresh, modular approaches to drug discovery.
科研通智能强力驱动
Strongly Powered by AbleSci AI