卤化
化学
区域选择性
醋酸
戒指(化学)
反应条件
有机化学
催化作用
作者
Kenneth J. Hoffmann,Per H. J. Carlsen
标识
DOI:10.1080/00397919908086142
摘要
Abstract Bromination in concentrated solutions of substituted thiophenes in acetic acid with NBS at room temperature was studied. Under the conditions, bromination readily took place with high regioselectivity at the 2-ring positions, > 99 %. The developed method was demonstrated to be suitable for multimolar preparations.
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