Hormonal and radiographic features of primary empty sella

Clinical data of 116 cases diagnosed as primary empty sella (PES) from 2012 to 2016 in the Department of Endocrine and Metabolic Diseases, Ruijin Hospital were analyzed in this study. Insulin-induced hypoglycemia test and magnetic resonance imaging (MRI) were applied to explore the predictive factors of hypopituitarism in patients with PES. The results showed that 43 (37.07%) patients with PES were with hypopituitarism. Pituitary height<2.35 mm and pituitary sagittal area<23.5 mm2 indicated a high risk of hypopituitarism in patients with PES. (Chin J Endocrinol Metab, 2017, 33: 849-853) Key words: Primary empty sella; Pituitary-secreting hormone deficiency; Insulin-induced hypoglycemia test