In order to observe the biological effect of rare earth (RE) on Corynebacterium glutamicum S(9114), the effects of single compound CeCl(3) on the growth of Corynebacterium glutamicum S(9114) and the enzymatic activities of glutamate dehydrogenase ( GDH )and lactate dehydrogenase ( LDH ) were studied. The results showed that CeCl(3) accelerated the growth of Corynebacterium glutamicum S(9114) at low dosage range, but inhibited the growth when the dosage increased to certain content. The same effect was also observed for the enzymatic activities of GDH and LDH.