This review discusses recent approaches to novel nanomaterials used for construction of electrochemiluminescence immunosensors since 2006.Described approaches relying on nanoparticles and carbon nanotubes' specific surface,biocompatibility and conduction activity,not only enhance their electrochemiluminescent intensity but also decrease their ECL starting potential.The approaches would promote the application of nanomaterials in fabricating electrochemiluminescence immunosensors for chemical and biochemical analysis.The nanocomposite consisted of quantum dots,nanoparticles and carbon nanotube can provide a new idea for developing novel electrochemiluminescence immunosensors.