Longitudinal Analysis of Changes in Deep Learning Image-based Breast Cancer Risk Scores over Time

< .001). The findings were consistent across subgroups. Conclusion AI-based risk scores from screening mammograms evolved over time and diverged between women who did and did not develop breast cancer, supporting their potential as dynamic biomarkers for risk-adaptive screening and prevention strategies. © RSNA, 2026 See also the editorial by Mann and Wang in this issue.