Direct influence of systemic desensitization by resiniferatoxin on the activities of Aδ‐ and C‐fibers in the rat primary bladder mechanosensitive afferent nerves

The present results show the existence of resiniferatoxin desensitization-resistant mechanosensitive Aδ- and C-fibers in rat primary bladder afferent nerves, suggesting that systemic resiniferatoxin treatment might induce non-specific partial desensitization or denervation of mechanosensitive capsaicin-insensitive Aδ- and C-fibers of the rat bladder.