脑深部刺激
穹窿
内侧前脑束
医学
认知功能衰退
刺激
痴呆
阿尔茨海默病
神经学
内科学
心理学
疾病
海马体
精神科
帕金森病
纹状体
多巴胺
作者
Andrés M. Lozano,Lisa Fosdick,M. Mallar Chakravarty,Jeannie‐Marie Leoutsakos,Cynthia A. Munro,Esther S. Oh,Kristen E. Drake,Christopher H. Lyman,Paul B. Rosenberg,William S. Anderson,David F. Tang‐Wai,J. Cara Pendergrass,Stephen Salloway,Wael F. Asaad,Francisco A. Ponce,Anna Burke,Marwan N. Sabbagh,David A. Wolk,Gordon H. Baltuch,Michael S. Okun
摘要
DBS for AD was safe and associated with increased cerebral glucose metabolism. There were no differences in cognitive outcomes for participants as a whole, but participants aged≥65 years may have derived benefit while there was possible worsening in patients below age 65 years with stimulation.
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