单链
高分子化学
纳米颗粒
链条(单位)
化学工程
化学
材料科学
纳米技术
高分子科学
工程类
物理
天文
抗体
免疫学
生物
作者
Abdalrahman U. Alrayyes,Karteek Boga,Mark Louis P. Vidallon,Huanting Wang,Kei Saito
标识
DOI:10.1002/macp.202300081
摘要
Abstract Herein, a novel, highly branched and photoresponsive polysiloxane is synthesized and studied. The polymer is photo‐constructed into a single‐chain nanoparticle loaded with Nile Red and Metformin. Through the photoreversible [2+2] mechanism of the polymer's pendant coumarin moieties, the nanoparticles are de‐crosslinked, and their cargo molecules released. A study of the kinetics of release is undertaken in different solvents, providing insight into the relationship between the cargo's molecular structure and that of the polymer chain. On the whole, this report's study introduces new controlled release and cationic ring‐opening polymerization concepts while providing the first example of a single‐chain polymer nanoparticle based on a photoresponsive polysiloxane. This article is protected by copyright. All rights reserved
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