医学
巩膜炎
视力模糊
彭布罗利珠单抗
病变
眼科
中止
外科
葡萄膜炎
内科学
癌症
免疫疗法
作者
Calvin L. McNelly,Asghar Haider,Robert C Wann,Jason N. Crosson,John O. Mason
标识
DOI:10.1177/24741264231163396
摘要
Purpose: To report a case of painless posterior scleritis presenting as a choroidal nodule in a patient with history of a tumor being treated with pembrolizumab. Methods: A case and its findings were analyzed, and a relevant literature review was performed. Results: A 20-year-old woman with a history of ependymoma presented with painless blurred vision in the right eye after being started on pembrolizumab for a tumor recurrence. Fundoscopy showed a solitary amelanotic choroidal lesion with surrounding subretinal fluid in the affected eye. Ultrasonography showed moderate internal reflectivity and fluid in Tenon capsule consistent with nodular posterior scleritis. After a course of systemic steroids and discontinuation of the pembrolizumab, the choroidal lesion completely resolved. Conclusions: Clinicians should be aware of posterior scleritis as an ocular complication of this class of medications.
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