L-Proline Catalyzed Organic Reactions via Microwave-Activation

Abstract: In the past few years, using microwave power to heat and wield chemical reactions has be-come a gradually more popular subject in the scientific community. Microwave-supported organic syn-thesis is confirmed to be involved in rapidly synthesizing novel compounds with selectivity and en-hanced biological activities. Microwave flash heating for chemical synthesis is a spectacular reduction in reaction times, high yield and purity of the products, etc. A catalysis field wherein small organic mol-ecules like L-Proline efficiently and selectively catalyzes organic transformations. Microwave-assisted L-Proline catalyzed reactions are valuable tools for making different acyclic, heterocycles, and carbocy-clic scaffolds that signify the main framework of most bioactive compounds. In synthetic organic chem-istry, microwave irradiation speedily discarded the conventional heating methods in the world of multi-component and step-wise synthetic chemistry. This review discusses only L-Proline Catalyzed Organic Reactions under microwave activation using modern organic transformations, including condensation, addition, asymmetric, multi-components, and other modular reactions.