医学
平衡
基因
节奏
细胞生物学
内科学
心脏病学
遗传学
生物
作者
Mason Sweat,Wei Shi,Yan Y. Sweat,Jie Li,Jiajin Li,Erin Keating,Anna Ponek,Qing Ma,C. Park,Michael A. Trembley,Yi Wang,Cuilan Hou,Vassilios J. Bezzerides,Frank L. Conlon,William T. Pu
出处
期刊:Circulation
[Lippincott Williams & Wilkins]
日期:2025-08-13
卷期号:152 (11): 784-801
被引量:3
标识
DOI:10.1161/circulationaha.125.073833
摘要
Our findings reveal that normal atrial rhythm requires CHD4, which activates and represses atrial genes in a context-dependent manner to maintain aCM gene expression, aCM identity, and atrial rhythm homeostasis.
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