A near-infrared and lysosome-targeted BODIPY photosensitizer for photodynamic and photothermal synergistic therapy

A multifunctional BODIPY derivative Lyso-BDP was prepared. It shows near-infrared absorption and emission, photosensitizing activity, lysosomal targeting, and synergistic PDT and PTT effects, and kills cancer cells both in vitro and in vivo .