Y2O3 ceramics has various applications. Choosing raw powders and control of their properties is crucial for obtaining full transparency. In this research, the influence of the milling conditions of Y2O3 powders on the characteristic of vacuum-sintered ceramics was studied. The milling was performed at a rate of 80-300 rpm for 1-22 h. It was found that milling at 300 rpm for 1 h gives the most promising nano-sized Y2O3 powder. The highest transmittance among obtained samples is 78.3% (1100 nm).