医学
皮肤病科
病因学
结缔组织病
穿孔
结缔组织
疾病
病理
自身免疫性疾病
冶金
材料科学
冲孔
作者
Spencer P. McClure,William Liakos,Edward W. Seger,Maryam Abdo,Anne-Marie Murray,Ryan Gillihan
摘要
Acquired reactive perforating collagenosis is an uncommon disorder that present as keratotic plugs on the skin owing to transepidermal perforation of dermal connective tissue. Etiology is unclear, although the condition has been associated with renal disease, diabetes, and HIV. It can frequently be misdiagnosed and lead to significant impact on quality of life, particularly in patients with skin of color. Herein, we present an skin of color patient with this condition who experienced severe pruritus over years before receiving a definitive diagnosis. Clobetasol improved her condition and quality of life over several months.
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