炎症体
药理学
医学
机制(生物学)
信号转导
药效学
汤剂
作用机理
肺
炎症
呼吸系统
免疫学
细胞损伤
发病机制
炎症反应
癌症研究
动物模型
体外
作者
Baojun Xu,Yuejie Wang,Yang Xu,Xinjie Zhang,Xiaoya Wang,Siyu Chen,Lijing Li,Huiwei Bao
标识
DOI:10.1016/j.jep.2025.120908
摘要
This study investigated the pharmacodynamics and mechanism of SBPD in treating respiratory inflammation. SBPD protected mice against LPS-induced ALI by alleviating lung tissue damage. Through integrated investigation of the complete formulation and the monomer baicalin, it was collaboratively demonstrated that SBPD exerts anti-inflammatory effects via the NLRP3 inflammasome pathway.
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