Cerebral embolic protection devices in transcatheter aortic valve implantation: a systematic review and meta-analysis of randomized controlled trials

CEPD did not significantly reduce the incidence of ischemic lesions or neurocognitive decline. Current evidence does not support a statistically significant clinical benefit of CEPD use during TAVI. While trends suggest a potential reduction in stroke, larger trials are needed to establish the significance of these results.