Chemical constituents from Lagopsis supina and their chemotaxonomic significance

Phytochemical study on the whole plant Lagopsis supina led to the isolation of twenty-nine compounds, which consist of five triterpenoids (1–5), six steroids (6–11), three phenylpropanoids (12–14), two flavonoids (15–16), five fatty acid derivatives (17–21), one dipeptide (22), one sesquiterpenoid (23), and six phenols (24–29). Their structures were elucidated based on analysis of spectroscopic data and comparison with literature data. In this work, compounds 1–3, 12–14, 19, 21, and 24 are reported from the Lamiaceae family for the first time, while all compounds except 5, 9 and 15 are reported from the Lagopsis genus for the first time. Compounds 17, 18 and 20 were previously obtained through synthetic methods only, and are therefore discovered as natural products for the first time. Moreover, the chemotaxonomic significance of the isolated compounds is discussed.