医学
心力衰竭
收缩性
心脏病学
内科学
心脏再同步化治疗
射血分数
耐火期
耐火材料(行星科学)
药物治疗
刺激
物理
天体生物学
作者
Alexander Wallner,Salvatore Savona,Rami Kahwash
标识
DOI:10.1016/j.hfc.2023.05.006
摘要
Cardiac contractility modulation (CCM) is a novel therapeutic approach for heart failure patients, which utilizes nonexcitatory electrical myocardial stimulation in the absolute refractory period of the cardiac cycle. This stimulation has been shown to increase contractility , leading to improved heart failure symptoms, functional status, and quality of life . CCM is FDA approved for heart failure patients with an LVEF between 25% and 45% who remained symptomatic despite optimal medical therapy and not candidate of cardiac resynchronization therapy. CCM offers expanded treatment options for heart failure patients who have continued symptoms while on optimal medical therapy.
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