伏格特-小柳-原田病
医学
眼科
视力
浆液性液体
荧光血管造影
视网膜
吲哚青绿
视网膜色素上皮
吲哚青绿血管造影
外科
葡萄膜炎
病理
作者
Aniruddha Agarwal,K. Bailey Freund,Aman Kumar,Kanika Aggarwal,Deeksha Sharma,Deeksha Katoch,Reema Bansal,Vishali Gupta
出处
期刊:Retina-the Journal of Retinal and Vitreous Diseases
[Ovid Technologies (Wolters Kluwer)]
日期:2020-08-18
卷期号:41 (4): 774-783
被引量:34
标识
DOI:10.1097/iae.0000000000002914
摘要
Purpose: To report the frequency, optical coherence tomography (OCT) findings, and visual and anatomic outcomes of patients with acute Vogt–Koyanagi–Harada disease presenting with the bacillary layer detachment (BLD) (intraretinal split at the photoreceptor inner segment myoid). Methods: This was a retrospective analysis of a consecutive series of patients with Vogt–Koyanagi–Harada disease having a minimum follow-up of 6 months. All patients had swept-source OCT, fluorescein angiography, and indocyanine green angiography performed at baseline. The characteristics of serial swept-source OCT were recorded and analyzed. Results: Sixty-two subjects (42 women; age: 34.2 ± 12 years) with Vogt–Koyanagi–Harada disease were included. 118 eyes (95.2%) had serous retinal detachment at presentation. 112 eyes (94.9%) showed the BLD at baseline. In 8 of 112 (7.1%) eyes with the BLD, the external limiting membrane at the anterior aspect of the BLD showed focal discontinuity. The interdigitation zone at the base of the BLD showed discontinuity in 53 of 112 (47.3%) eyes with the BLD. The ellipsoid zone could not be identified as a separate hyperreflective line at the base of the BLD in 102 of 112 eyes (91.1%). Bacillary layer detachments resolved within 3.4 ± 1.3 days after intravenous methylprednisolone therapy with improvement in the best-corrected visual acuity from 0.96 to 0.4 logarithm of the minimum angle of resolution (20/184 Snellen's equivalent) ( P < 0.001). Resolution of serous retinal detachment was observed after 5.9 ± 2.6 days. Conclusion: In eyes with acute Vogt–Koyanagi–Harada disease, the BLD is a common finding and represents a split in the photoreceptor layer at the inner segment myoid and can be differentiated from serous retinal detachment using swept-source OCT. In addition, resolution of the BLD and photoreceptor recovery can be evaluated using serial swept-source OCT.
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