The Clinical Effectiveness Of Thalidomide Combined With Low Dose Dexamethasone On Multiple Myeloma

Objective To observe the effectiveness of thalidomide combined with low dose dexamethasone on patients with multiple myeloma (MM).Methods 16 cases with MM were enrolled for studies.Among them,9 cases are initial treament and 7 cases are relapsed or/ and refractory patient s.The dosage of thalidomide was 150mg/d,the administerd dosage of dexamethasone was 10～20 mg/dfor d 1-4 ,d 9-12 ,d 17-20 every month.Results Among the 16 evaluable patients,3 of them achieved complete remission (CR),6 of them achieved partial remission ( PR), 3 of them showed partial improving and 4 of them had no effects. Side effects could been tolerate.Conclusion Thalidomide Combined With Low Dose Dexamethasone might be effective in these patients with relapsed or/ and refractory MM,as well as these patients with initial treatment MM.