Clinical Effect of Granisetron Combined with Dexamethasone in Control Vomiting caused by Cisplatin

Objective To study the anti vomiting effect of granisetron combined with dexamethasonum.Methods Fifty seven patients received cisplatin chemotherapy were randomly divided into two groups,granisetron group and granisetron with dexamethasone group.Cross contrast was used to compare the effect of granisetron and granisetron combined with dexamethasonum.Results The complete control rates of acute vomiting were 68.5% in granisetron group alone,and 89.4% in granisetron plus dexamethasonum group ( P 0 005),there was statistically different.Conclusions Granisetron combined with dexamethasone can remarkably improve the efficacy of control of acute vomting induced by cisplation.