Objective: To investigate the curative effect of metoprolol combined with amiodarone in patients with congestive heart failure and taehyarrhythmia. Methods: A total of 43 NYHA class Ⅱ-Ⅳpatients with CHF complicated by ventricular arrhythmia were randomly divided into amiodarone group and amiodarone + metoprolol group. The therapeutic effects were evaluated. Results: The clinical effective rate was 90%(18/20) in amiodarone + metoprolol group,while that was 60. 87%(14/23) in amiodarone group,the difference was statistically significant(P 0. 05). Conclusion: The combination of amiodarone and metoprolol could produce better effect than amiodarone alone in the treatment of CHF complicated by ventricular arrhythmia.