This paper adopts the non-uniform rational B-spline(NURBS)to express the geometry of ship hull and the grids generated by the method are directly used in the calculation for hydrodynamic performance of hull.The wave-making resistance and maneuvering hydrodynamics of a Wigley ship at an attack angle with an approximate Kuta condition are numerically computed by using the present method.The comparison of experimental results,shows that the method has engineering precision and a positive effect for the mutual integration between computer aided design(CAD)and computational fluid dynamics(CFD)in the naval architecture and ocean engineering.