In order to compare the performance of the vortex induced vibrations(VIV) of twin-box bridge sections in different Reynolds numbers,two groups of experiments with 40 cases were carried out in TJ-1 and TJ-3 wind tunnel.The results show that VIV occurs in a more widely range of damping ratios with rather larger amplitudes in the low Reynolds number experiments.While in the high Reynolds number experiments,VIV only occurs in a much closer range of damping ratios with the amplitude being smaller.As for the guide vanes,they do decrease the amplitude of VIV in the attack angle of zero no matter the Reynolds number is high or low.However,when the attack angle exists,they only can decrease the amplitudes in the high Reynolds number experiments while the amplitudes of VIV will be increased a lot in the low Reynolds number experiments.Comparisons are also done with the experiments of the Great Belt East Bridge and the Stonecutters Bridge.The mechanisms of the experiments are detailed hereafter together with the reasons of comparisons' divergence and agreement.