A porcine reproductive and respiratory syndrome virus(PRRSV) strain isolated from visceral organs was designated as PRRSV-FS.The sequence analysis revealed that the isolated virus was a mutation strain as the Nsp2 gene existed amino acid deletion of 30 and the GP5 gene was conservative relatively.The genome of PRRSV FS strain showed 88.7%,98.8%,58.5% of nucleotide indentity with ATCC VR-22332,JN-HS,Europena Lelystad virus respectively.