Clinical application comparsion of transrectal 6+X and 14+X core prostate biopsy for the diagnosis of prostate cancer

Objective To compare the prostate cancer detection rate(PCDR)and complications of transrectal 6+X and 14+X core prostate biopsy. Methods We retrospectively analyzed 384 cases who underwent transrectal prostate biopsy for suspected prostate cancer.From January 2007 to April2009,106 patients were given transrectal finger guided 6+X core prostate biopsy and chosen as control group,the observation group include 278 patients who were given transrectal ultrasound guided14+X core prostate biopsy between May 2009 and December 2014. Results The PCDR of the control group was 32.1%(34/106),obviously lower than 47.5%(142/278)of the observation group(P0.05).The PCDR of the prostate ultrasound hypoechoic area in observation group was 60.3%(47/78).However,the PCDR of the finger touch prostate nodule area in control group was 86.4%(19/22),which was higher than that of the observation group(P0.05).The positive rate of hematuria in the control group and observation group were 11.3%(12/106)and 4.7%(13/278),respectively.And the difference of the positive rate of hematuria between the two groups was statistically significant(P0.05).The incidence rates of post biopsy infection and rectal bleeding of the two groups had no statistical significant difference(all P0.05).Severe adverse reactions such as septic shock,sepsis,vasovagal reflex were not found in the two groups. Conclusions Transrectal finger guided 6+X core prostate biopsy and transrectal ultrasound guided 14+X core prostate biopsy are both safe and elfective for the diagnosis of prostate cancer.The latter can improve the PCDR without increasing complications.