Vanilloid (TRPV1) and Other Transient Receptor Potential Channels

This chapter contains sections titled: Overview Introduction Temperature-sensitive TRP (thermoTRP) channels are multifaceted sensors TRPV1, the archetypal thermoTRP channel, is activated by capsaicin and endovanilloids TRPV1 antagonists: a preclinical overview TRPV2, a structural homolog of TRPV1 TRPV3, a warm-sensitive relative of TRPV1 TRPV4, a polymodal channel with a widespread diversity of activation mechanisms TRPA1, the cold receptor highly coexpressed with the hot TRPV1 TRPM8, the cool menthol receptor Conclusions References