医学
乳腺摄影术
乳腺癌
乳腺癌筛查
乳腺X光筛查
妇科
人口
癌症
随机对照试验
临床试验
肿瘤科
内科学
环境卫生
出处
期刊:Climacteric
[Informa]
日期:2018-01-17
卷期号:21 (3): 204-208
被引量:9
标识
DOI:10.1080/13697137.2017.1392503
摘要
The evidence is reviewed on the efficacy and effectiveness of mammography screening derived from randomized screening trials and from the surveillance of populations where mammography screening for breast cancer has been introduced. Nearly all the trials were performed in the era before modern adjuvant therapy for breast cancer was introduced, apart from the Canadian National Breast Screening Study and the UK Age trial. The former found no benefit from annual mammography screening for 5 years in women age 40–59 years, the latter, a non-significant benefit from screening women by annual mammography for 7 years from ages 39 to 41 years. The evidence from population-based surveillance is mixed, most such studies having failed to consider the benefit gained from improved therapy. It is concluded that we have reached the point of negligible benefit from mammography screening for breast cancer in women at average risk, and that we should concentrate on early diagnosis of breast cancer and the application of modern therapy according to clearly defined sub-types of breast cancer.
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