化学
均分解
磷化氢
催化作用
药物化学
磷酸化
亲电芳香族取代
激进的
组合化学
高分子化学
有机化学
生物化学
作者
Jianxin Cao,Tong‐Hao Zhu,Zhongwei Gu,Wen‐Juan Hao,Shun‐Yi Wang,Shun‐Jun Ji
出处
期刊:Tetrahedron
[Elsevier]
日期:2014-09-01
卷期号:70 (39): 6985-6990
被引量:45
标识
DOI:10.1016/j.tet.2014.07.078
摘要
A silver-catalyzed 2-isocyanobiaryls insertion/cyclization with phosphine oxides was described for the construction of the 6-phosphorylated phenanthridines through radical addition of in situ formed P-centered radical to 2-isocyanobiphenyls and homolytic aromatic substitution process. The reactions could proceed smoothly to give the desired 6-phosphorylated phenanthridines promoted by AgOAc (20 mol %) with PhI(OAc)2 (3.0 equiv).
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