Effect of substitution on reactivity of some alkyl halides in the reaction with sodium thiosulphate

Abstract A comparison of the rate of displacement of halide ion by thiosulphate ion in alkyl halides, namely n‐amyl iodide, n‐hexyl iodide, n‐heptyl iodide, n‐octyl iodide, n‐amyl bromide, isoamyl bromide, sec‐amyl bromide and n‐amyl chloride at different temperatures and in varying alcohol‐water mixtures has been made. In the case of n‐amyl halides, there is a much larger rate difference between chloride and bromide than between bromide and iodide.