核心
功能(生物学)
生物
神经科学
细胞核
核运输
计算生物学
细胞生物学
作者
Angus I. Lamond,William C. Earnshaw
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:1998-04-24
卷期号:280 (5363): 547-553
被引量:886
标识
DOI:10.1126/science.280.5363.547
摘要
Current evidence suggests that the nucleus has a distinct substructure, albeit one that is dynamic rather than a rigid framework. Viral infection, oncogene expression, and inherited human disorders can each cause profound and specific changes in nuclear organization. This review summarizes recent progress in understanding nuclear organization, highlighting in particular the dynamic aspects of nuclear structure.
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