Handbook of Drug Screening

Key Factors for Successful High-Throughput Screening, John G. Houston Critical Components in High-Throughput Screening: Challenges and New Trends, Litao Zhang, Martyn N. Banks, and John G. Houston Hit-to-Probe-to-Lead Optimization Strategies: A Biology Perspective to Conquer the Valley of Death, Anuradha Roy, Byron Taylor, Peter R. McDonald, Ashleigh Price, and Rathnam Chaguturu Signal Detection Platforms for Screening in Drug Discovery, Ramakrishna Seethala Proteomic Analysis in Drug Discovery, Haiteng Deng, Yang Xu, and Linqi Zhang Screening and Characterization of G-Protein-Coupled Receptor Ligands for Drug Discovery, Ge Zhang and Mary Ellen Cvijic Nuclear Hormone Receptor Screening in Drug Discovery, Ramakrishna Seethala and Litao Zhang Emerging Novel High-Throughput Screening Technologies for Cell-Based Assays, Ilona Kariv, Alexander A. Szewczak, Nathan W. Bays, Nadya Smotrov, and Christopher M. Moxham In Vitro Strategies for Ion Channel Screening in Drug Discovery, Ravikumar Peri, Mark Bowlby, and John Dunlop Wheat from Chaff: General andMechanistic Triage of Screening Hits for Enzyme Targets, Mark R. Harpel Protein Kinases and Phosphatases, Pirthipal Singh MicroRNA Strategies in Drug Discovery, Wishva B. Herath, Dwi S. Karolina, Arunmozhiarasi Armugam, and Kandiah Jeyaseelan Strategies for Screening of Biologic Therapeutics, Ian Foltz and Francesca Civoli Cryopreserved Cells in Functional Cell-Based HTS Assays, Geetha Shankar and Kirk McMillan High-Content Screening with a Special Emphasis on Cytotoxicity and Cell Health Measurementsn Ralph J. Garippa and Ann F. Hoffman Effective Application of DrugMetabolism and Pharmacokinetics in Drug Discovery, Sharon Diamond and Swamy Yeleswaram Compound Management for Drug Discovery: An Overview, Moneesh Chatterjee and Martyn N. Banks Practical Approach to Quantitative High Throughput Screening, Wei Zheng, Ke Liu, and James Inglese Enabling the Large-Scale Analysis of Quantitative High-Throughput Screening Data, Noel T. Southall, Ajit Jadhav, Ruili Huang, Trung Nguyen, and Yuhong Wang Application of Nanobiotechnologies for Drug Discovery, K. K. Jain Index