奥斯特瓦尔德成熟
成核
聚结(物理)
膜
非平衡态热力学
斯莫鲁乔夫斯基凝聚方程
化学物理
动力学
物理
材料科学
热力学
凝聚态物理
经典力学
化学
生物化学
天体生物学
作者
Daniel P. Arnold,Aakanksha Gubbala,Sho C. Takatori
标识
DOI:10.1103/physrevlett.131.128402
摘要
Phase separation of multicomponent lipid membranes is characterized by the nucleation and coarsening of circular membrane domains that grow slowly in time as $\ensuremath{\sim}{t}^{1/3}$, following classical theories of coalescence and Ostwald ripening. In this Letter, we study the coarsening kinetics of phase-separating lipid membranes subjected to nonequilibrium forces and flows transmitted by motor-driven gliding actin filaments. We experimentally observe that the activity-induced surface flows trigger rapid coarsening of noncircular membrane domains that grow as $\ensuremath{\sim}{t}^{2/3}$, a $2\mathsf{x}$ acceleration in the growth exponent compared to passive coalescence and Ostwald ripening. We analyze these results by developing analytical theories based on the Smoluchowski coagulation model and the phase field model to predict the domain growth in the presence of active flows. Our Letter demonstrates that active matter forces may be used to control the growth and morphology of membrane domains driven out of equilibrium.
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