机械转化
生物
细胞生物学
细胞骨架
糖酵解
氧化磷酸化
磷酸化
新陈代谢
细胞
生物化学
作者
Logan W Dawson,Nicholas Cronin,Kris A. DeMali
标识
DOI:10.1016/j.ceb.2023.102219
摘要
Epithelial and endothelial cells experience numerous mechanical cues throughout their lifetimes. Cells resist these forces by fortifying their cytoskeletal networks and adhesions. This reinforcement is energetically costly. Here we describe how these energetic demands are met. We focus on the response of epithelial and endothelial cells to mechanical cues, describe the energetic needs of epithelia and endothelia, and identify the mechanisms these cells employ to increase glycolysis, oxidative phosphorylation, and fatty acid metabolism. We discuss the similarities and differences in the responses of the two cell types.
科研通智能强力驱动
Strongly Powered by AbleSci AI