Functional Imaging Constrained Diffusion for Brain PET Synthesis from Structural MRI

F-fluorodeoxyglucose (FDG)-PET scans suggest that FICD achieves superior performance in generating FDG-PET data compared to state-of-the-art methods. We further validate the effectiveness of the proposed FICD on data from a total of 1262 subjects through three downstream tasks, with experimental results suggesting its utility and generalizability.