脂肪变性
基因亚型
未折叠蛋白反应
发病机制
脂肪肝
内科学
内分泌学
医学
细胞生物学
生物
内质网
生物化学
基因
疾病
作者
Kuangyang Chen,Yahao Wang,Jia Yang,Nora Klöting,Chuanfeng Liu,Jiarong Dai,Shuoshuo Jin,Lijiao Chen,S. Liu,Yuzhao Liu,Yongzhuo Yu,Xiaoxia Liu,Qing Miao,Chong Wee Liew,Yangang Wang,Arne Dietrich,Matthias Blüher,Xuanchun Wang
标识
DOI:10.1016/j.jhep.2024.03.047
摘要
Endoplasmic reticulum (ER) membrane protein complex subunit 10 (EMC10) has been implicated in obesity. Here we investigated the roles of the two isoforms of EMC10, including a secreted isoform (scEMC10) and an ER membrane-bound isoform (mEMC10), in metabolic dysfunction-associated steatotic liver disease (MASLD).
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