生物
HDAC4型
癌症研究
染色质免疫沉淀
转录因子
胰腺癌
分子生物学
细胞生物学
组蛋白甲基转移酶
乙酰化
发起人
基因表达
癌症
生物化学
遗传学
基因
作者
Hao Yuan,Chuang Chen,Haonan Li,Gexi Qu,Luyao Chen,Yaxing Liu,Yufeng Zhang,Qiang Zhao,Changhong Lian,Aifang Ji,Xuedong Hou,Xinjian Liu,Kuirong Jiang,Yi Zhu,Yuan He
标识
DOI：10.1186/s12943-023-01923-7
摘要
Pancreatic cancer (PC) is an extremely malignant tumor with low survival rate. Effective biomarkers and therapeutic targets for PC are lacking. The roles of circular RNAs (circRNAs) in cancers have been explored in various studies, however more work is needed to understand the functional roles of specific circRNAs. In this study, we explore the specific role and mechanism of circ_0035435 (termed circCGNL1) in PC.
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