医学
效力
缺血性中风
内科学
冲程(发动机)
心脏病学
急性中风
急诊医学
缺血
机械工程
生物化学
化学
组织纤溶酶原激活剂
工程类
体外
作者
Juxian Gu,Chao Liu,Yan Yao
出处
期刊:Biomarkers in Medicine
[Future Medicine]
日期:2024-03-05
标识
DOI:10.2217/bmm-2023-0545
摘要
Objective: This study aimed to investigate the prognostic potency of LRG1 in acute ischemic stroke (AIS) patients. Methods: Plasma LRG1 levels were detected at admission and on days 3, 7 and 30 in 150 AIS patients. Results: LRG1 positively correlated with total cholesterol (p = 0.016), triglycerides (p = 0.046), C-reactive protein (p < 0.001), TNF-α (p = 0.001) and IL-6 (p = 0.004). After admission, LRG1 showed a decreasing trend (p < 0.001). Interestingly, LRG1 levels at admission (p = 0.014), day 3 (p = 0.027), day 7 (p = 0.008) and day 30 (p = 0.002) were higher in patients with modified Rankin scale score ≥2 versus those with scores <2. The LRG1 levels at day 7 (p = 0.032) and day 30 (p = 0.023) were higher in patients with recurrence versus no recurrence. Conclusion: LRG1 correlates with blood lipids, inflammation and short-term prognosis of AIS.
科研通智能强力驱动
Strongly Powered by AbleSci AI