Effect of esketamine as an adjuvant of ropivacaine on the efficacy of supraclavicular brachial plexus block in radius fracture surgery: a randomized controlled trial

Adding 25 mg esketamine to 30 mL of 0.4% ropivacaine did not improve the analgesic efficacy of SBPB in patients undergoing distal radius fracture surgery. These findings suggest that the limited benefits of esketamine in peripheral nerve blocks such as SBPB warrant further investigation to optimize agent design.