医学
免疫系统
趋化因子
炎症
发病机制
单克隆抗体
免疫学
淋巴细胞
渗透(HVAC)
T淋巴细胞
体内
抗体
病理
生物
生物技术
物理
热力学
作者
Gaurav Malviya,Filippo Galli,Ida Sonni,Alberto Signore
出处
期刊:PubMed
日期:2014-09-01
卷期号:58 (3): 237-57
被引量:15
摘要
Increasing interest and research efforts have been made in search of specific radiolabelled probes for imaging different immune cells (including T-lymphocytes) in inflammation and infection. This has led to early detection of lymphocyte infiltration, and the deepening of our understanding of pathogenesis of immune mediated diseases. In-vivo imaging of T-lymphocytes with radiolabelled specific probes may provide an important piece of information about inflammatory lesions, which could be very important to understand the molecular mechanism of action of any drug and/or their effect on the microenvironment of the immune system of the body. The present review focuses on radiolabelled T-lymphocytes and different monoclonal antibodies, peptides, cytokines, chemokine used for scintigraphic imaging of T-lymphocytes and their subsets.
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