Preparation and biocompatibility research of modified PPC biomaterial

Objective To study the preparation and biocompatibility of modified poly(propylene carbonate)(M-PPC) so as to provide experimental reference for its clinical applicationMethods M-PPC was generated by blending of PPC and PHB.The biocompatibility evaluation experiments included cell toxicity test by MTT and implantational test of M-PPC.Results All the test results showed that M-PPC induced no cytotoxicity to Hela cell,and M-PPC had good biocompatibility in vivo and in vitro.Conclusion M-PPC is one new kind of safe medical materials which has good biocompatibility.