Inhibition of NADPH Oxidase-4 Potentiates 2-Deoxy- d -Glucose-Induced Suppression of Glycolysis, Migration, and Invasion in Glioblastoma Cells: Role of the Akt/HIF1α/HK-2 Signaling Axis

In summary, the combined inhibition of Nox-4 and glycolysis may have therapeutic implications for the management of GBMs.