固相萃取
聚合物
材料科学
核化学
色谱法
原子转移自由基聚合
高效液相色谱法
检出限
傅里叶变换红外光谱
分散性
聚合
乙二醇
大小排阻色谱法
化学
高分子化学
化学工程
有机化学
复合材料
工程类
酶
作者
Shaodan Zhou,Jiaqi Tang,Bo Jia,Yunkai Lü
出处
期刊:Sepu
[China Science Publishing & Media Ltd.]
日期:2018-01-01
卷期号:36 (2): 85-85
标识
DOI:10.3724/sp.j.1123.2017.10026
摘要
Activators regenerated by electron transfer-atom transfer radical polymerization (ARGET-ATRP) was applied to the continuous grafting of polybasic polymers and poly(ethylene glycol) (PEG) brushes on the surface of the magnetic microspheres (MMs). At first, the MMs were coated with silica gel, modified by amino group, and then 2-bromoisobutyryl bromide was grafted on the surface of MMs. After that, the hydrophilic polymer brushes magnetic microspheres (HMMs) were prepared by polymerization on the surface of the MMs. HMMs were characterized by transmission electron microscope (TEM) and Fourier transform-infrared (FT-IR) spectrometer. The adsorption performance to protein was studied. The results demonstrated that HMMs have the relatively uniform particle size, good dispersity and excellent protein resistance properties. Tetracycline antibiotics (TCs, tetracycline hydrochloride, chlortetracycline hydrochloride and doxycycline hydrochloride) in honey samples were determined by magnetic dispersion solid phase extraction (MDSPE) using the prepared HMMs and high performance liquid chromatography (HPLC). The average recoveries were obtained in the range of 85.8%-94.5%. The limits of detection (LODs) and limits of quantification (LOQs) of the proposed method were in the ranges of 1.92-2.56 μg/kg and 6.40-8.53 μg/kg, respectively. The proposed method was successfully applied to fast clean-up and enrichment of the TCs residues in honey.
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