Enantioselective synthesis of gem -diarylalkanes by transition metal-catalyzed asymmetric arylations (TMCAAr)

-diarylalkane compounds. The main methodology includes enantioselective 1,2- or 1,4-additions across C[double bond, length as m-dash]O, C[double bond, length as m-dash]N and C[double bond, length as m-dash]C bonds by arylmetallic reagents; aryl cross-couplings of olefins, benzylic (pseudo)halides and aziridines; asymmetric aryl substitution reactions of allylic substrates; and isotopic benzylic C-H arylation.