脱毛
强脉冲光
医学
毛发生长
腋窝
随机对照试验
通量
毛囊
绒毛
皮肤病科
激光治疗
激光器
牙科
外科
内科学
生理学
光学
头皮
乳腺癌
癌症
物理
作者
Daniel Thaysen‐Petersen,M. Barbet-Pfeilsticker,Frank Beerwerth,J. Frank Nash,Peter A. Philipsen,Petra Staubach,Merete Hædersdal
摘要
Background At-home laser and intense pulsed-light hair removal continues to grow in popularity and availability. A relatively limited body of evidence is available on the course of hair growth during and after low-fluence laser usage. Objectives To assess growing hair counts, thickness and colour quantitatively during and after cessation of low-fluence laser treatment. Methods Thirty-six women with skin phototypes I–IV and light to dark-brown axillary hairs were included. Entire axillary regions were randomized to zero or eight self-administered weekly treatments with an 810-nm home-use laser at 5·0–6·4 J cm−2. Standardized clinical photographs were taken before each treatment and up to 3 months after the final treatment for computer-aided quantification of growing hair counts, thickness and colour. Results Thirty-two women completed the study protocol. During sustained treatment, there was a reduction in growing hair that reached a plateau of up to 59%, while remaining hairs became up to 38% thinner and 5% lighter (P < 0·001). The majority of subjects (77%) reported ‘moderately’ to ‘much less hair’ in treated than untreated axilla, and assessed remaining hairs as thinner and lighter (≥ 60%). After treatment cessation, hair growth gradually returned to baseline levels, and 3 months after the final treatment the count and thickness of actively growing hair exceeded pretreatment values by 29% and 7%, respectively (P ≤ 0·04). Conclusions Sustained usage of low-fluence laser induced a stable reduction of growing hair counts, thickness and colour. The reduction was reversible and hairs regrew beyond baseline values after cessation of usage. Computer-aided image analysis was qualified for quantification of hair counts, thickness and colour after laser epilation.
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